August 20, 2021
Nervous system disorders include abnormalities in either function or structure of the central or peripheral nervous system. These illnesses might be the result of trauma, metabolic dysfunction, infection or genetic conditions. A large number of scientific studies and discoveries aim to reduce the impacts and frequency of neurological disorders, mental health, and drug abuse.
Herbal medicines and natural products were used in ancient therapies. During the last decades, researchers focused more on herbs in drug discovery because of their limited side effects and fewer complications. According to the improving demand, the medicinal and pharmacological studies have been increasing worldwide.
Rosemary (Rosmarinus officinalis L.) is an evergreen bushy shrub which grows along the Mediterranean Sea, and sub-Himalayan areas. In folk medicine, it has been used as an antispasmodic, mild analgesic, to cure intercostal neuralgia, headaches, migraine, insomnia emotional upset, and depression. Different investigations have highlighted rosemary neuropharmacological properties as their main topics. Rosemary has significant antimicrobial, anti-inflammatory, anti-oxidant, anti-apoptotic, anti-tumorigenic, antinociceptive, and neuroprotective properties. Furthermore, it shows important clinical effects on mood, learning, memory, pain, anxiety, and sleep.
Recent studies showed that the main ethnopharmacological uses of rosemary have been confirmed by neuropharmacological investigations. According to these researches, the most important components of rosemary which are medicinally and pharmacologically active are rosmarinic acid, carnosic acid, and the essential oil. These compounds can provide promising natural medicines in the treatment of the nervous system pathological conditions including anxiety, depression, Alzheimer’s disease, epilepsy, Parkinson’s disease, and withdrawal syndrome.