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Ginger Essential Oil for Prevention of Multiple Sclerosis

January 30, 2025

Multiple sclerosis is a debilitating condition where the myelin sheath that covers nerve cells is damaged disrupting nervous system signals and resulting in numbness, tingling, mood changes, memory problems, pain, fatigue, blindness and/or paralysis. Multiple sclerosis (MS) affects each person differently, with some symptoms being temporary and others long-lasting and more severe. The exact cause of Multiple sclerosis is not known, but, genetic factors and environmental exposures can be introduced as a reason. Currently, there is no definite cure for Multiple sclerosis (MS), therefore, finding a fully effective and safe treatment has been widely considered. Some drugs such as fingolimod are used in clinic. The reason for choosing fingolimod as a standard drug is that it has been shown to cross the blood-brain barrier using radiolabeling, and this drug can prevent demyelination of axon fibers, and inhibit lymphocyte proliferation, and it has anti-inflammatory properties. Similar to the function of fingolomod, the essential oil of ginger was reported to have the properties of the blood-brain barrier action, anti-inflammatory and antioxidant properties and in general its neuroprotective properties.

January 15, 2025

Dental caries and periodontal diseases are identified as the most important among oral health problems globally. Oral diseases adversely affect the general health too. Quality of life and the working capacity of an individual are also affected. The antibacterial agents that are currently used for treatment of oral health problems are reported to cause several side effects such as diarrhea, vomiting, etc., Increasing bacterial resistance to the drugs is also a major concern. Because of the adverse effects, increasing bacterial resistance, and high cost associated with the standard therapeutic procedure, there is a need to explore new therapeutic agents and conduct further clinical research on traditional medicines obtained from various plant sources.

January 1, 2025

Acetaminophen (e.g., Tylenol, Paracetamol) is the number one cause of acute liver failure in the USA, Canada, and UK. Exceeding 3,250 mg to 3,900 mg (depending on the type and strength) per day can cause liver harm. Acute liver failure can happen after one very large dose of acetaminophen, or after higher than recommended doses every day for several days. Curcumin, a major bioactive compound in turmeric herb, is known for its anti-inflammatory and antioxidant activity, which helps protect tissues and organs. Curcumin is well-recognized for its hepatoprotective activity, which was emphasized using different in vivo hepatic injury and hepatic carcinoma models such as alcohol-induced hepatic fibrosis, aflatoxin-induced liver injury heavy metals-induced liver damage, and paracetamol (Para) induced liver toxicity.

December 20, 2024

Fatigue refers to a state of prolonged or temporary physical or mental weakness and exhaustion, often accompanied by a lack of energy, motivation, and attention. It can be caused by various factors, including excessive physical activity, prolonged cognitive or emotional stress, inadequate sleep, poor nutrition, chronic illnesses, medication side effects, and more, severely impacting people's health, quality of life, and work efficiency. Nowadays, fatigue is not only a suboptimal state of health but can also lead to a range of diseases such as Alzheimer's disease, obesity, anxiety disorders, poor sleep quality, and depression.

December 7, 2024

Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that has been recognized as the key cause of dementia in elderly people. According to the latest data from Centers for Disease Control and Prevention (CDC), 121,499 people died due to AD in 2019. Currently, there is no definite cure for the treatment of AD due to its multi-factorial nature. Therefore, phytotherapy profiting from valuable biological activities of a mixture of constituents has been in the center of attention. Focusing on the herbal remedies used in the treatment of AD , essential oils (EOs) were found to be very effective since various in vitro, in vivo, and clinical trials have endorsed their efficacy because of low molecular weight and high hydrophobicity leading to easy crossing the blood-brain barrier (BBB).

Essential Oils are naturally occurring secondary metabolites which contain a complex mixture of volatile compounds possessing a wide range of biological activities. It should be noted that aromatherapy using plants such as Cinnamomum verum J. Presl. (Lauraceae), Myrtus communis L. (Myrtaceae), Ruta graveolens L. (Rutaaceae), Anethum graveolens L. (Apiaceae), Myristica fragrans Houtt. (Myristicaceae), and Crocussativus L. (Iridaceae) has been traditionally recommended for the treatment of memory loss in Iranian traditional medicine (ITM). On the other hand, non-pharmacological approaches have been developed for the improvement of cognitive problems and in this respect, aromatherapy has been widely considered as a strong tool. In different studies, the combination of therapies has depicted significant results in improving memory, quality of life, and treatment of other complications in patients with AD.

Ginger Essential Oil for Prevention of Multiple Sclerosis

Essential oils, their therapeutic properties, and implication in dentistry: A review

The Synergistic Hepatoprotective Activity of Rosemary Essential Oil and Curcumin

Evaluation of Schisandra chinensis extract on anti-fatigue activity

Cinnamon Bark essential oil (Cinnamomum verum) : in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity

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